Drug disposition property optimization
- Physico-chemical properties optimization
- Log D
- Permeability
- Solubility
- In vitro drug metabolism
- Plasma protein binding
- Metabolic stability
- CYP inhibition and Induction
- Drug transporters
- Drug – Drug Interaction (DDI) prediction: Devise plans to assess mechanistic based clinical drug-drug interaction risk potential of a drug candidate with respect to
- Direct inhibition, mechanistic based inhibition and induction
- Drug transporter
- Metabolite identification